Analytical Data
-
Gene name
CCNDBP1
- Application
-
Alternative Names
AU022347; CCDB1_HUMAN; CCNDBP 1; Ccndbp1; Cyclin D type binding Protein 1; Cyclin-D1-binding Protein 1; D type cyclin interacting Protein 1; DIP 1; DIP1; GCIP; Grap 2 and cyclin D interacting Protein; Grap 2 cyclin D interacting Protein GCIP
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
O95273
-
Expression Region
1-360aa
-
AA Sequence
MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMCHLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL
-
Molecular Weight
66.7 KDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCNDBP1, or CCN domain-binding protein 1, is a member of the CCN (connective tissue growth factor, cysteine-rich protein 61, and Nov) family of proteins, which are known for their roles in cell proliferation, differentiation, and extracellular matrix regulation. Research has shown that CCNDBP1 is implicated in various cellular processes, including regulation of gene expression and cellular signaling pathways, and is associated with several physiological and pathological conditions, such as tissue repair and cancer progression. The protein has garnered interest due to its potential as a biomarker for certain diseases as well as its significance in understanding cell behavior in development and disease contexts. Despite its functional importance, studies on CCNDBP1 have been limited by the lack of sufficient quantities of the protein for detailed biochemical analyses. Therefore, recombinant expression of CCNDBP1 in suitable host organisms, such as bacteria or eukaryotic cells, represents a promising approach to producing this protein at scale. This methodology can facilitate the study of CCNDBP1's structure, function, and interactions, thereby advancing our understanding of its role in health and disease. Consequently, the research on the recombinant protein provides essential insights that can lead to therapeutic advancements, making CCNDBP1 a significant focus in the field of molecular biology and cancer research.
