Analytical Data
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Gene name
CCDC37
- Application
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Alternative Names
CFAP100; CCDC37Cilia- and flagella-associated Protein 100; Coiled-coil domain-containing Protein 37
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q494V2
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Expression Region
1-611aa
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AA Sequence
MSEIPSTIVSKNMTNDKNSLESMNISSSSSTEENPKKQARKNEEHGPDPSANPFHLSGDVDFFLLRDQERNKALSERQQQKTMRVHQKMTYSSKVSAKHTSLRRQLQLEDKQEDLEARAEAEHQRAFRDYTTWKLTLTKEKNVEPENMSGYIKQKRQMFLLQYALDVKRREIQRLETLATKEEARLERAEKSLEKDAALFDEFVRENDCSSVQAMRAAEKETKAKIEKILEIRDLTTQIVNIKSEISRFEDTLKHYKVYKDFLYKLSPKEWLEEQEKKHSFLKKAKEVSEASKESSVNSTPGDKGPGIKGKASSMWAKEGQGTKKPWRFLQTMRLGRSPSYLSSPQQGSQPSESSGGDSRGSNSPIPPTQEDTDSDGEEPQLYFTEPQQLLDVFRELEEQNLSLIQNSQETEKTLEELSHTLKHTQIRMDREVNQLKQWVTTMMMSITKEEDTAAELELKARVFHFGEYKGDQQDKLLESLNCKVLDVYRHCTGTQQEANLGTVQMLTIIEHQLDELLENLEHVPQVKIEQAERAKEKERRIRLREEKLQMQKILQEEHLQRARARAQAEIKKKRGRTLVCRSRPPAHRIKQQSEHTLMDKEEEELLFFFT
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Molecular Weight
97.5 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC37, or Coiled-Coil Domain Containing 37, is a protein that plays a vital role in various cellular processes, including protein stabilization and regulation of protein interactions. Recent studies have highlighted its involvement in the assembly of protein complexes, particularly in the context of molecular chaperones and protein degradation pathways. Given its potential implications in disease mechanisms, including cancer and neurodegenerative disorders, reconstitution of CCDC37 as a recombinant protein has become a pivotal area of research. Researchers aim to explore its structural characteristics, functional roles, and interaction partners through reconstitution techniques, allowing for a better understanding of its biological significance. The production of CCDC37 in a recombinant form not only facilitates the study of its biochemical properties but also enables high-throughput screening for potential therapeutic targets. By elucidating the mechanisms by which CCDC37 functions within cellular environments, scientists hope to uncover novel insights into its contributions to pathophysiology and its potential as a biomarker or therapeutic target in various diseases. This research, therefore, stands at the intersection of structural biology, biochemistry, and translational medicine, offering a promising avenue for future discoveries in the field of molecular biology.
