Analytical Data
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基因名
CD63
- Application
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别名
CD63；MLA1；TSPAN30；CD63 antigen
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P08962
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表达区间
2-238aa
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氨基酸序列
AVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSGYEVM
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分子量
31.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD63, a member of the tetraspanin family, is a type III membrane protein widely expressed in various cell types, including immune and hematopoietic cells. It plays a pivotal role in the regulation of cellular processes such as adhesion, migration, and signaling. Notably, CD63 is involved in the formation and function of exosomes, which are small extracellular vesicles that facilitate intercellular communication and transport biomolecules. Increased expression of CD63 has been associated with various pathological conditions, including cancer and autoimmune diseases, making it a potential biomarker for disease progression and diagnosis. The production of recombinant CD63 protein is crucial for studying its structure, function, and interactions with other proteins. Such research can provide insights into the molecular mechanisms underlying its role in health and disease, paving the way for therapeutic applications. Moreover, recombinant CD63 can be utilized in the development of diagnostic tools and targeted therapies, highlighting its significance in biomedical research.
