Analytical Data
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Gene name
CCDC138
- Application
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Alternative Names
CCDC138; Coiled-coil domain-containing Protein 138
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96M89
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Expression Region
1-577aa
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AA Sequence
MEPRVVKPPGQDLVVESLKSRYGLGGSCPDEYDFSNFYQSKYKRRTLTSPGDLDIYSGDKVGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQLQWMPFVNIKLHEPFVKFIYWSLRQLDAGAQHSTMTSTLRRLGEDIFKGVVTKGIQDNSPQHSVENKPKTAAFFKSSNLPLRFLSTLIVLKTVTQADYLAQAFDSLCLDLKTEEGKTLFLEYQAVPVILSHLRISSKGLLSNVIDSLLQMTVESRVIRSSLNFLRFI
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Molecular Weight
92.8 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC138 is a protein that has attracted research interest due to its potential role in various biological processes and diseases. It is known to be involved in cellular mechanisms such as cilia formation, and its dysfunction has been linked to developmental disorders and respiratory diseases. Recent studies have suggested that CCDC138 may play a critical role in the assembly of ciliary structures, which are essential for cell signaling and maintaining proper cellular function. The understanding of CCDC138 is further enhanced by its association with specific genetic mutations leading to ciliary dysfunction and related syndromes, such as primary ciliary dyskinesia (PCD). Given the importance of cilia in numerous physiological processes, including reproduction and neurology, elucidating the structure and function of CCDC138 is crucial for developing potential therapeutic strategies. Researchers are focusing on producing recombinant CCDC138 proteins to study their functional properties and interaction with other cellular components. This research is anticipated to provide insights into the molecular pathways involving CCDC138, potentially leading to new diagnostics or treatments for diseases associated with ciliary dysfunction. Thus, CCDC138 remains a promising target for further investigation in the fields of cell biology and medical research.
