Analytical Data
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Gene name
RHEBL1
- Application
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Alternative Names
RHEBL1; GTPase RhebL1; Ras homolog enriched in brain like-1 c; RhebL1c; Ras homolog enriched in brain-like protein 1; Rheb-like protein 1; Rheb2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TAI7
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Expression Region
1-180 aa
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AA Sequence
MPLVRYRKVV ILGYRCVGKT SLAHQFVEGE FSEGYDPTVE NTYSKIVTLG KDEFHLHLVD TAGQDEYSIL PYSFIIGVHG YVLVYSVTSL HSFQVIESLY QKLHEGHGKT RVPVVLVGNK ADLSPEREVQ AVEGKKLAES WGATFMESSA RENQLTQGIF TKVIQEIARV ENSYGQERRC
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Molecular Weight
20.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RHEBL1 is a member of the Rho GTPase family, implicated in various cellular processes, including cell signaling, cytoskeletal dynamics, and cell migration. Research into RHEBL1 has gained traction due to its potential roles in both normal cellular functions and pathological conditions, such as cancer and neurodegenerative diseases. The protein's structure allows it to act as a molecular switch, cycling between active and inactive states, which is crucial for mediating downstream effects on target proteins. Understanding the regulatory mechanisms governing RHEBL1 activity can shed light on its involvement in cellular pathways that govern proliferation and differentiation. Furthermore, given its potential link to disease states, RHEBL1 has emerged as a candidate for therapeutic intervention. Recent studies have focused on characterizing its biochemical properties and interactions with other proteins, as well as exploring its effects in various cellular contexts. The development of recombinant RHEBL1 proteins has facilitated these investigations, allowing for detailed mechanistic analyses and providing insights into its functional roles. Comprehensive studies on RHEBL1 not only enhance our understanding of Rho GTPases but also offer promising avenues for targeting this protein in disease treatment strategies.
