Cat: PAX2000-10887

Recombinant Human RHCG Protein,GST

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Analytical Data

  • Gene name

    RHCG

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Ammonium transporter Rh type C; C15orf6; CDRC2; chromosome 15 open reading frame 6; PDRC2; Rh family type C glycoprotein; Rh glycoprotein kidney; Rh type C glycoprotein; rhcg; RHCG_HUMAN; Rhesus blood group family type C glycoprotein; Rhesus blood group; C glycoprotein; RHGK; SLC42A3; Tumor-related protein DRC2

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9UBD6

  • Expression Region

    1-479 aa

  • AA Sequence

    MAWNTNLRWRLPLTCLLLQVIMVILFGVFVRYDFEADAHWWSERTHKNLSDMENEFYYRYPSFQDVHVMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFLQDRYIVVGVENLINADFCVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAVNEFILLNLLKVKDAGGSMTIHTFGAYFGLTVTRILYRRNLEQSKERQNSVYQSDLFAMIGTLFLWMYWPSFNSAISYHGDSQHRAAINTYCSLAACVLTSVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMMLMPYGALIIGFVCGIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGIVGAVTAASASLEVYGKEGLVHSFDFQGFNGDWTARTQGKFQIYGLLVTLAMALMGGIIVGLILRLPFWGQPSDENCFEDAVYWEMPEGNSTVYIPEDPTFKPSGPSVPSVPMVSPLPMASSVPLVP

  • Molecular Weight

    79.6 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

RHCG (Rhesus-associated Glycoprotein) is part of the Rhesus blood group system and plays a crucial role in ammonia transport across cell membranes. It is primarily expressed in the kidneys and the central nervous system and contributes to maintaining acid-base balance and nitrogen homeostasis. Research into RHCG has gained prominence due to its integral function in renal physiology and the potential implications of its dysregulation in various pathophysiological conditions, such as metabolic acidosis and renal diseases. Furthermore, the study of RHCG is essential for understanding its interactions with other transport proteins and its role in the immune response. The recombinant protein produced from RHCG can be used to investigate its structural properties and functional mechanisms, providing insights into its physiological roles and potential therapeutic targets. Understanding RHCG’s biophysical characteristics through recombinant technologies may pave the way for novel strategies in treating related disorders and enhance our comprehension of ammonia transport processes in mammals. Additionally, advancements in recombinant protein expression techniques have enabled researchers to produce RHCG in sufficient quantities for biochemical and biophysical analysis, facilitating a deeper exploration of its significance in health and disease.

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