Analytical Data
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Gene name
CBARA1
- Application
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Alternative Names
CALC; calcium binding atopy related autoantigen 1; Calcium uptake Protein 1; calcium uptake Protein 1. mitochondrial ; Calcium-binding atopy-related autoantigen 1; CBARA1; EFHA3; FLJ12684; MICU1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BPX6
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Expression Region
1-476aa
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AA Sequence
MFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEKKTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFDGKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKDMGFTRLMQAMWKCAQETAWDFALPKQ
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Molecular Weight
80.8 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CBARA1, or the CBARA1 gene product, is a protein of significant interest in the field of molecular biology and biomedical research due to its potential roles in various cellular processes and its implications in disease. Initially identified through genomic studies, CBARA1 has been linked to key regulatory functions in apoptotic pathways, cellular stress responses, and immune modulation. Researchers have noted its involvement in the signaling pathways that govern cell survival and differentiation, making it a candidate for further exploration in cancer biology and therapeutic targeting. Additionally, studies have suggested that aberrations in CBARA1 expression levels may correlate with specific pathological conditions, including autoimmune disorders and malignancies. The recombinant production of CBARA1 has facilitated detailed structural and functional analyses, enabling scientists to investigate its interactions with other proteins and its overall role in cellular dynamics. Understanding the molecular mechanisms governed by CBARA1 could reveal novel insights into disease mechanisms and aid in the development of innovative therapeutic strategies. Consequently, ongoing research focuses on elucidating the biological significance of CBARA1, which may lead to breakthroughs in the diagnosis and treatment of related diseases.
