Analytical Data
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Gene name
PSG6
- Application
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Alternative Names
PSG6；CGM3；PSG10；PSG12；Pregnancy-specific beta-1-glycoProtein 6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q00889
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Expression Region
35-435aa
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AA Sequence
QVIIEA KPPKVSEGKD VLLLVHNLPQ NLTGYIWYKG QMTDLYHYIT SYVVHGQIIY GPAYSGRETV YSNASLLIQN VTQEDAGSYT LHIIKRGDGT GGVTGYFTVT LYSETPKPSI SSSNLNPREV MEAVRLICDP ETPDASYLWL LNGQNLPMTH RLQLSKTNRT LYLFGVTKYI AGPYECEIRN PVSASRSDPV TLNLLPKLPM PYITINNLNP REKKDVLAFT CEPKSRNYTY IWWLNGQSLP VSPRVKRPIE NRILILPSVT RNETGPYQCE IRDRYGGIRS NPVTLNVLYG PDLPRIYPSF TYYRSGENLD LSCFADSNPP AEYSWTINGK FQLSGQKLFI PQITTNHSGL YACSVRNSAT GKEISKSMIV KVSETASPQV TYAGPNTWFQ EILLL
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The PSG6 protein, a member of the Pregnancy-Specific Glycoprotein (PSG) family, plays a crucial role in human placentation and immunological tolerance during pregnancy. PSGs are primarily produced by trophoblast cells and are believed to contribute to the successful establishment and maintenance of pregnancy by modulating the maternal immune response, allowing for the acceptance of the semi-allogenous fetus. PSG6, in particular, has garnered attention due to its unique expression pattern and potential involvement in various pathological conditions, including pregnancy-related complications such as preeclampsia and intrauterine growth restriction. Research on PSG6 has focused on its immunomodulatory properties, signaling pathways, and interaction with other proteins, aiming to elucidate its exact biological functions and potential therapeutic applications. Given the increasing prevalence of reproductive health issues and the importance of maternal-fetal health, understanding PSG6 may provide valuable insights into both normal pregnancy physiology and the underlying mechanisms of pregnancy disorders, thereby informing the development of novel diagnostic and treatment strategies.
