Analytical Data
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Gene name
RAB11B
- Application
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Alternative Names
RAB11B；YPT3；Ras-related Protein Rab-11B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15907
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Expression Region
2-215aa
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AA Sequence
GTRDDEYDYL FKVVLIGDSG VGKSNLLSRF TRNEFNLESK STIGVEFATR SIQVDGKTI KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE NVERWLKELR DHADSNIVIM LVGNKSDLR HLRAVPTDEA RAFAEKNNLS FIETSALDST NVEEAFKNIL TEIYRIVSQK QIADRAAHD ESPGNNVVDI SVPPTTDGQK PNKLQCC
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Molecular Weight
26 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB11B is a member of the RAB family of small GTPases, which are critical regulators of intracellular membrane traffic and organelle dynamics. It plays a significant role in various cellular processes, including endocytosis, exocytosis, and the recycling of membrane proteins. Research has shown that RAB11B is involved in the regulation of vesicle transport to the plasma membrane, influencing processes such as cell migration, polarization, and receptor recycling. Its dysregulation has been linked to several diseases, including cancer and neurodegenerative disorders, which has generated interest in understanding its molecular function and potential as a therapeutic target. Researchers have increasingly focused on producing recombinant RAB11B for structural and functional studies, using techniques such as protein expression in various systems, including bacteria and eukaryotic cells. The study of RAB11B recombinant protein aims to elucidate its role in cellular pathways and how it interacts with other proteins and membrane compartments. By characterizing RAB11B at the molecular level, scientists hope to gain insights into its involvement in disease processes and to identify potential strategies for intervention. The ongoing research into RAB11B continues to contribute to a broader understanding of membrane trafficking mechanisms and their implications in health and disease.
