Analytical Data
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基因名
RAB11B
- Application
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别名
RAB11B;YPT3;Ras-related Protein Rab-11B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15907
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表达区间
2-215aa
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氨基酸序列
GTRDDEYDYL FKVVLIGDSG VGKSNLLSRF TRNEFNLESK STIGVEFATR SIQVDGKTI KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE NVERWLKELR DHADSNIVIM LVGNKSDLR HLRAVPTDEA RAFAEKNNLS FIETSALDST NVEEAFKNIL TEIYRIVSQK QIADRAAHD ESPGNNVVDI SVPPTTDGQK PNKLQCC
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB11B is a member of the RAB family of small GTPases, which are critical regulators of intracellular membrane traffic and organelle dynamics. It plays a significant role in various cellular processes, including endocytosis, exocytosis, and the recycling of membrane proteins. Research has shown that RAB11B is involved in the regulation of vesicle transport to the plasma membrane, influencing processes such as cell migration, polarization, and receptor recycling. Its dysregulation has been linked to several diseases, including cancer and neurodegenerative disorders, which has generated interest in understanding its molecular function and potential as a therapeutic target. Researchers have increasingly focused on producing recombinant RAB11B for structural and functional studies, using techniques such as protein expression in various systems, including bacteria and eukaryotic cells. The study of RAB11B recombinant protein aims to elucidate its role in cellular pathways and how it interacts with other proteins and membrane compartments. By characterizing RAB11B at the molecular level, scientists hope to gain insights into its involvement in disease processes and to identify potential strategies for intervention. The ongoing research into RAB11B continues to contribute to a broader understanding of membrane trafficking mechanisms and their implications in health and disease.












