Cat: PAX2000-10855

Recombinant Human REXO1L1 Protein,His

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Analytical Data

  • Gene name

    REXO1L1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    REXO1L1P; GOR; REXO1L1Putative exonuclease GOR; EC 3.1.-.-; Antigen GOR homolog; RNA exonuclease 1 homolog-like 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8IX06

  • Expression Region

    1-675 aa

  • AA Sequence

    MLRATAPCWF PPGYPEAKKV AEEAALEASR HLGGEQSQAG APEGSKMLRA TAPCWFRPGY PEAKKVAKEA APEASRHLGA EQSPAGAPEG SKMLRATAPC WFPPGYPEAK KVAEEAALEA PEFPLPSHQP AQSFGLWVPQ MHKQASAFVD IQAEPQNRGP AVPPAWPKMV TESCYFPAQR GSACRLPAAP RLTERPSGVR ISAPRKRKTI AHSSSPCLVT GYTDAKRTRV ASSSQRSRGS KVGRQPGKTR NRSGMACKTT ATTSSKRIVR RASLPSLSLK KPIILRSSGC QVPTVLRRGY LQLFTEECLK FCASKQEAEE KALNEEKVAY DCSPNKNRYL NVVLNTLKRL KGLTPSSMPG LSRAALYSRL QEFLLTQDQL KENGYPFPHP ERPGGAVLFT GQGKGPGDSS CRVCCRCGTE YLVSSSGRCV RDQLCYYHWG RVRSSQVAGG RVSQYTCCAA APGSVGCQVA KQHVRDGRKE SLDGFVETFK KELSRDAYPG IYALDCEMCY TTHGLELTRV TVVDADMRVV YDTFVKPDNE IVDYNTRFSG VTEADVAKTS ITLPQVQAIL LSFFSAQTIL IGHSLESDLL ALKLIHSTVV DTAVLFPHYL GFPYKRSLRN LAADYLAQII QDSQDGHNSS EDASACLQLV MWKVRQRAQI QPRHRSASPA ALACP

  • Molecular Weight

    73.8 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

REXO1L1 (RNA exonuclease 1 homolog 1) plays a crucial role in RNA metabolism, particularly in the processing and degradation of RNA molecules, which is vital for gene expression regulation and RNA quality control. Its involvement in the RNA decay pathways highlights its potential significance in various biological processes, including development and differentiation. Research into REXO1L1 has gained momentum due to its implications in cellular responses to stress and its possible associations with diseases, including cancers and genetic disorders. The study of recombinant REXO1L1 proteins aims to elucidate the enzyme's biochemical properties, substrate specificity, and interaction with other cellular components. Understanding the functional mechanisms of REXO1L1 at the molecular level can provide insights into its role in RNA metabolism and disease pathology. Furthermore, the development of recombinant proteins allows for detailed kinetic studies and structural analyses, facilitating the identification of potential therapeutic targets. Consequently, REXO1L1 represents a promising candidate for further investigation in the context of RNA biology and therapeutic development.

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