Analytical Data
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基因名
FZD6
- Application
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别名
FZD6；Frizzled-6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60353
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表达区间
71-181aa
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氨基酸序列
PNIETFLCKAFVPTCIEQIHVVPPCRKLCEKVYSDCKKLIDTFGIRWPEE LECDRLQYCDETVPVTFDPHTEFLGPQKKTEQVQRDIGFWCPRHLKTSGG QGYKFLGIDQC
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分子量
38 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FZD6, or Frizzled Class Receptor 6, is a member of the Frizzled family of G-protein-coupled receptors that play a crucial role in the Wnt signaling pathway, which is essential for various biological processes, including cell proliferation, differentiation, and embryonic development. The dysregulation of Wnt signaling has been implicated in several diseases, particularly cancer. Research into FZD6 has gained attention due to its potential as a therapeutic target, as well as its involvement in stem cell regulation and tissue homeostasis. Recombinant FZD6 proteins are being studied to elucidate their structure-function relationships and to better understand how they interact with Wnt ligands and other signaling molecules. The production of FZD6 recombinant proteins facilitates the exploration of its role in cellular signaling, providing insights into the mechanisms of Wnt-related diseases and aiding in the identification of novel drug candidates. Furthermore, understanding the molecular characteristics and binding properties of FZD6 can enhance our knowledge of its involvement in developmental processes and tumorigenesis, thus paving the way for the development of targeted therapies aimed at modulating the Wnt pathway in various pathologies.
