Analytical Data
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Gene name
PMAP23
- Application
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Alternative Names
PMAP23；Antibacterial peptide PMAP-23
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Species
Pig
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P49930
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Expression Region
131-153aa
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AA Sequence
RIIDLLWRVRRPQKPKFVTVWVR
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Molecular Weight
19.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PMAP23, or Porcine/Mammalian Antimicrobial Peptide 23, is a notable antimicrobial peptide that has garnered significant attention in biomedical research due to its potential therapeutic applications. This peptide, derived from porcine sources, exhibits a broad spectrum of antimicrobial activities against various pathogens, including bacteria, fungi, and even certain viruses. The increasing prevalence of antibiotic resistance has prompted the urgent need for alternative antimicrobial strategies, positioning PMAP23 as a promising candidate. Research has indicated that PMAP23 functions through multiple mechanisms, such as disrupting microbial membranes and modulating immune responses, thereby enhancing its efficacy. Furthermore, its relatively low cytotoxicity in mammalian cells suggests a favorable safety profile, making it an attractive option for both veterinary and human medicine. Studies are actively exploring the optimization of PMAP23 through genetic engineering and synthetic biology approaches to improve its stability, efficacy, and delivery systems. As we advance our understanding of its structure-function relationships and mechanisms, PMAP23 could play a pivotal role in developing novel therapies to combat infections, particularly in an era where conventional antibiotics are becoming less effective. Overall, the research on PMAP23 not only highlights the importance of antimicrobial peptides in addressing global health challenges but also opens new avenues for innovation in antimicrobial drug development.
