Analytical Data
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基因名
RCBTB1
- Application
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别名
Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; CLLL7; CLLL7 protein; E4.5; GDP/GTP exchange factor (GEF) like protein; GLP; Guanine nucleotide exchange factor; Hypothetical protein FLJ39335; RCBT1_HUMAN; Rcbtb1; RCC1 and BTB domain-containing protein 1; Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; Regulator of chromosome condensation and BTB domain-containing protein 1; RP11-185C18.1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NDN9
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表达区间
1-531 aa
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氨基酸序列
MVDVGKWPIF TLLSPQEIAS IRKACVFGTS ASEALYVTDN DEVFVFGLNY SNCLGTGDNQ STLVPKKLEG LCGKKIKSLS YGSGPHVLLS TEDGVVYAWG HNGYSQLGNG TTNQGIAPVQ VCTNLLIKQV VEVACGSHHS MALAADGEVF AWGYNNCGQV GSGSTANQPT PRKVTNCLHI KRVVGIACGQ TSSMAVLDNG EVYGWGYNGN GQLGLGNNGN QLTPVRVAAL HSVCVNQIVC GYAHTLALTD EGLLYAWGAN TYGQLGTGNK NNLLSPAHIM VEKERVVEIA ACHSAHTSAA KTQGGHVYMW GQCRGQSVIL PHLTHFSCTD DVFACFATPA VSWRLLSVEH EDFLTVAESL KKEFDSPETA DLKFRIDGKY IHVHKAVLKI RCEHFRSMFQ SYWNEDMKEV IEIDQFSYPV YRAFLQYLYT DTVDLPPEDA IGLLDLATSY CENRLKKLCQ HIIKRGITVE NAFSLFSAAV RYDAEDLEEF CFKFCINHLT EVTQTAAFWQ MDGPLLKEFI AKASKCGAFK N
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分子量
58.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RCBTB1 (Regulator of Chromatin Binding Transcription Factor 1) is a protein that has garnered interest due to its role in various cellular processes, particularly those related to chromatin remodeling and gene regulation. This protein is known to be involved in maintaining genomic integrity and influencing cellular responses to stress. Recent studies have suggested that RCBTB1 may play a critical role in cancer biology, as it participates in pathways that modulate cell proliferation and apoptosis. The understanding of RCBTB1's mechanism of action could provide insights into its potential as a therapeutic target. Researchers are actively exploring the structural and functional aspects of RCBTB1, particularly through the study of its recombinant protein. By producing and analyzing recombinant RCBTB1, scientists aim to investigate its interactions with other proteins, its enzymatic activities, and its role in chromatin dynamics. This research has the potential to uncover novel regulatory mechanisms governing gene expression and to facilitate the development of targeted therapies for diseases, including cancer. Furthermore, as the elucidation of RCBTB1's functional roles progresses, it may also contribute to a better understanding of other related proteins within the chromatin remodeling complex, thus paving the way for future studies in epigenetics and cellular response mechanisms. Advances in recombinant protein technology and structural biology techniques will be essential in addressing the outstanding questions regarding RCBTB1's functions and implications in health and disease.
