Analytical Data
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Gene name
RBM48
- Application
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Alternative Names
RBM48; C7orf64; HSPC304; RNA-binding protein 48
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5RL73
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Expression Region
1-367 aa
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AA Sequence
MASSGGELGS LFDHHVQRAV CDTRAKYREG RRPRAVKVYT INLESQYLLI QGVPAVGVMK ELVERFALYG AIEQYNALDE YPAEDFTEVY LIKFMNLQSA RTAKRKMDEQ SFFGGLLHVC YAPEFETVEE TRKKLQMRKA YVVKTTENKD HYVTKKKLVT EHKDTEDFRQ DFHSEMSGFC KAALNTSAGN SNPYLPYSCE LPLCYFSSKC MCSSGGPVDR APDSSKDGRN HHKTMGHYNH NDSLRKTQIN SLKNSVACPG AQKAITSSEA VDRFMPRTTQ LQERKRRRED DRKLGTFLQT NPTGNEIMIG PLLPDISKVD MHDDSLNTTA NLIRHKLKEV ISSVPKPPED KPEDVHTSHP LKQRRRI
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Molecular Weight
41.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RBM48, an RNA-binding protein, plays a crucial role in various cellular processes, including mRNA regulation, splicing, and translation. Research has shown that RBM48 is involved in the development and differentiation of various tissues, particularly in the context of neuronal and muscle cell function. Its dysregulation has been implicated in several diseases, including neurodegenerative disorders and certain cancers. Understanding the functional mechanisms of RBM48 at the molecular level is essential for elucidating its role in health and disease. Recent studies have focused on elucidating the structural properties and interaction networks of RBM48, providing insights into its specific binding sites and target RNAs. Moreover, the generation of recombinant RBM48 proteins has facilitated in vitro studies, enabling researchers to investigate the protein's activity and specificity. This research not only enhances our comprehension of post-transcriptional regulation but also opens potential avenues for therapeutic interventions, where manipulating RBM48 function could provide novel strategies for treating related diseases.
