Cat: PAX2000-10805

Recombinant Human RBM47 Protein,His

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Analytical Data

  • Gene name

    RBM47

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    NET18; Rbm47; Rbm47 RNA binding motif protein 47 ; RBM47_HUMAN; RNA binding motif protein 47; RNA binding protein 47; RNA-binding motif protein 47; RNA-binding protein 47

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    A0AV96

  • Expression Region

    1-593 aa

  • AA Sequence

    MTAEDSTAAM SSDSAAGSSA KVPEGVAGAP NEAALLALME RTGYSMVQEN GQRKYGGPPP GWEGPHPQRG CEVFVGKIPR DVYEDELVPV FEAVGRIYEL RLMMDFDGKN RGYAFVMYCH KHEAKRAVRE LNNYEIRPGR LLGVCCSVDN CRLFIGGIPK MKKREEILEE IAKVTEGVLD VIVYASAADK MKNRGFAFVE YESHRAAAMA RRKLMPGRIQ LWGHQIAVDW AEPEIDVDED VMETVKILYV RNLMIETTED TIKKSFGQFN PGCVERVKKI RDYAFVHFTS REDAVHAMNN LNGTELEGSC LEVTLAKPVD KEQYSRYQKA ARGGGAAEAA QQPSYVYSCD PYTLAYYGYP YNALIGPNRD YFVKAGSIRG RGRGAAGNRA PGPRGSYLGG YSAGRGIYSR YHEGKGKQQE KGYELVPNLE IPTVNPVAIK PGTVAIPAIG AQYSMFPAAP APKMIEDGKI HTVEHMISPI AVQPDPASAA AAAAAAAAAA AAVIPTVSTP PPFQGRPITP VYTVAPNVQR IPTAGIYGAS YVPFAAPATA TIATLQKNAA AAAAMYGGYA GYIPQAFPAA AIQVPIPDVY QTY

  • Molecular Weight

    64.0 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RBM47 (RNA Binding Motif Protein 47) is a member of the RNA-binding protein family, playing a crucial role in post-transcriptional gene regulation. Research into RBM47 has surged due to its involvement in various biological processes, including RNA splicing, stability, and transport, as well as its implications in cellular responses to stress. Notably, aberrations in RBM47 expression levels have been linked to several diseases, including cancer, emphasizing its relevance in medical research. Recent studies have also highlighted its potential role in neurodevelopment and neurodegenerative disorders, attracting interest in understanding its molecular mechanisms. The recombinant expression of RBM47 allows for detailed functional analyses, aiding in the identification of its binding partners and elucidating its pathways in cellular mechanisms. Such research is essential for revealing the broader implications of RBM47 in health and disease, and for exploring its potential as a therapeutic target. Thus, investigating the recombinant protein RBM47 not only enhances our understanding of fundamental biological processes but also paves the way for novel approaches in disease treatment.

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