Analytical Data
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Gene name
RBM34
- Application
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Alternative Names
KIAA0117; Rbm34; RBM34_HUMAN; RNA binding motif protein 34; RNA-binding motif protein 34; RNA-binding protein 34
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P42696
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Expression Region
1-430 aa
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AA Sequence
MALEGMSKRK RKRSVQEGEN PDDGVRGSPP EDYRLGQVAS SLFRGEHHSR GGTGRLASLF SSLEPQIQPV YVPVPKQTIK KTKRNEEEES TSQIERPLSQ EPAKKVKAKK KHTNAEKKLA DRESALASAD LEEEIHQKQG QKRKNSQPGV KVADRKILDD TEDTVVSQRK KIQINQEEER LKNERTVFVG NLPVTCNKKK LKSFFKEYGQ IESVRFRSLI PAEGTLSKKL AAIKRKIHPD QKNINAYVVF KEESAATQAL KRNGAQIADG FRIRVDLASE TSSRDKRSVF VGNLPYKVEE SAIEKHFLDC GSIMAVRIVR DKMTGIGKGF GYVLFENTDS VHLALKLNNS ELMGRKLRVM RSVNKEKFKQ QNSNPRLKNV SKPKQGLNFT SKTAEGHPKS LFIGEKAVLL KTKKKGQKKS GRPKKQRKQK
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Molecular Weight
48.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RBM34 (RNA-binding motif protein 34) is a member of the RNA-binding motif protein family, characterized by its role in post-transcriptional regulation of gene expression. Research into RBM34 has gained traction due to its potential implications in various biological processes, including cellular differentiation, proliferation, and apoptosis. The protein is known to interact with specific RNA sequences, influencing mRNA stability and translation, thereby impacting protein synthesis. Aberrant expression of RBM34 has been implicated in several diseases, particularly cancer, where it may contribute to tumorigenesis by modulating the expression of key oncogenes and tumor suppressor genes. Moreover, studies have suggested that RBM34 might play a role in the regulation of immune responses, as its expression is found to be modulated in various immune cell types. Investigating the structural and functional characteristics of recombinant RBM34 protein is essential for understanding its molecular mechanisms and could provide insights into its potential as a therapeutic target or biomarker in disease contexts. Experimental approaches, including the generation of recombinant RBM34 proteins, allow for detailed studies of its RNA-binding capabilities and effects on gene regulation, fostering a deeper understanding of its biological significance.
