Analytical Data
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基因名
C9orf142
- Application
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别名
C9orf142; Chromosome 9 open reading frame 142 ; CI142_HUMAN; PAXX; Uncharacterized Protein C9orf142; XLS
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BUH6
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表达区间
1-204aa
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氨基酸序列
MDPLSPPLCT LPPGPEPPRF VCYCEGEESG EGDRGGFNLY VTDAAELWST CFTPDSLAAL KARFGLSAAE DITPRFRAAC EQQAVALTLQ EDRASLTLSG GPSALAFDLS KVPGPEAAPR LRALTLGLAK RVWSLERRLA AAEETAVSPR KSPRPAGPQL FLPDPDPQRG GPGPGVRRRC PGESLINPGF KSKKPAGGVD FDET
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分子量
48 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C9orf142, also known as chromosome 9 open reading frame 142, is a protein that has garnered interest due to its potential role in various biological processes, including cell proliferation and differentiation. Recent studies suggest that C9orf142 may be implicated in neurodegenerative diseases, specifically amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), owing to its association with genetic mutations linked to these conditions. Researchers are increasingly focused on understanding the function and mechanism of C9orf142, as insights into its structure and interactions could unveil critical pathways involved in disease pathogenesis. The production of recombinant C9orf142 protein is essential for elucidating its biochemical properties, stability, and interactions with other cellular components. By employing techniques such as recombinant DNA technology, scientists aim to generate sufficient quantities of this protein for in vitro and in vivo studies. This foundational research could pave the way for targeted therapeutic strategies and contribute to the broader understanding of genetic factors influencing neurodegeneration. Therefore, the study of C9orf142 not only enhances our comprehension of its biological role but also opens avenues for novel interventions in related health conditions.
