Analytical Data
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Gene name
RBM15B
- Application
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Alternative Names
RBM15B; OTT3; Putative RNA-binding protein 15B; One-twenty two protein 3; HsOTT3; HuOTT3; RNA-binding motif protein 15B
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NDT2
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Expression Region
1-563 aa
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AA Sequence
MPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA
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Molecular Weight
88.33 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RBM15B (RNA Binding Motif Protein 15B) is a member of the RBM15 family, which plays a crucial role in post-transcriptional gene regulation and RNA splicing. The protein has gained attention due to its involvement in various biological processes and diseases, including cancer and developmental disorders. Recent studies have highlighted RBM15B's function in regulating RNA stability and alternative splicing pathways, making it an important target for understanding the molecular mechanisms underlying these processes. Its association with hematological malignancies also emphasizes its potential as a therapeutic marker. Advances in recombinant protein technology have allowed for the production and characterization of RBM15B, providing insights into its structural and functional properties. By studying the recombinant RBM15B protein, researchers aim to elucidate its specific contributions to RNA metabolism and its interactions with other cellular components. Such investigations could pave the way for novel therapeutic strategies, targeting RBM15B-related pathways in diseases. Overall, the study of RBM15B recombinant protein represents a significant step toward deciphering the intricate roles of RNA-binding proteins in cellular regulation and disease pathogenesis.
