Cat: PA2000-6102

Recombinant Human C1orf14 Protein,His

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Analytical Data

  • Gene name

    C1orf14

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    1700012A16Rik; C1orf14; GE36; RGD1305609; RP5-1133A12.2; SHC binding and spindle associated 1 like; SHC SH2 domain-binding Protein 1-like Protein; SHCBP1L; SHP1L_HUMAN

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BZQ2

  • Expression Region

    1-725aa

  • AA Sequence

    MRPQDPALYP QAPHPLALGR ASHPSQSRNT PPAGRPRAAA RCGPERRAPI GQSGRGREKW PTAASALGLL RRWRRASKAS VPADSFRTIS PDRRGEKSAS AVSGDTAAAT TLKGTAIPVR SVVASPRPVK GKAGRETARL RLQRLPAAQA EDTGEAAAAA AEEPLLPVPE DEEEAQPLPP VCVSRMRGMW RDEKVSLYCD EVLQDCKAED ADEVMGKYLS EKLKLKDKWL GVWKTNPSVF FVKYEEASIP FVGILVEVTC EPYQDSSSRF KVTVSVAEPF SSNIANIPRD LVDEILEELE HSVPLLEVYP VEGQDTDIHV IALALEVVRF FYDFLWRDWD DEESCENYTA LIEERINLWC DIQDGTIPGP IAQRFKKTLE KYKNKRVELI EYQSNIKEDP SAAEAVECWK KYYEIVMLCG LLKMWEDLRL RVHGPFFPRI LRRRKGKREF GKTITHIVAK MMTTEMIKDL SSDTLLQQHG DLDLALDNCY SGDTVIIFPG EYQAANLALL TDDIIIKGVG KREEIMITSE PSRDSFVVSK ADNVKLMHLS LIQQGTVDGI VVVESGHMTL ENCILKCEGT GVCVLTGAAL TITDSEITGA QGAGVELYPG SIAILERNEI HHCNNLRTSN SSKSTLGGVN MKVLPAPKLK MTNNHIYSNK GYGVSILQPM EQFFIVAEEA LNKRASSGDK KDDKMLFKVM QNLNLEMNNN KIEANVKGDI RIVTS

  • Molecular Weight

    72.6 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

C1orf14, also known as Chromosome 1 Open Reading Frame 14, has attracted attention due to its potential roles in various biological processes and its implications in human health. This gene is located on chromosome 1 and encodes a protein that is involved in cellular functions, although its exact mechanisms remain largely unexplored. Recent studies have suggested that C1orf14 may play a role in neurodevelopment and the modulation of certain signaling pathways, which could link it to neurodegenerative diseases and other disorders. The interest in C1orf14 is further heightened by the discovery of its association with conditions such as cancer and autoimmune diseases, prompting researchers to delve deeper into its functional properties and expression patterns. Recombinant C1orf14 protein serves as a valuable tool in these investigations, enabling the elucidation of its structural characteristics and biological functions through in vitro assays. Understanding C1orf14's role in cellular processes could unveil new therapeutic targets and biomolecular pathways, contributing to advances in personalized medicine. As such, ongoing research into the recombinant expression, purification, and functional analysis of C1orf14 is crucial for revealing its significance in health and disease.

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