Analytical Data
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Gene name
C1orf149
- Application
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Alternative Names
MEAF6; C1orf149; CENP-28; EAF6Chromatin modification-related Protein MEAF6; MYST/Esa1-associated factor 6; Esa1-associated factor 6 homolog; Protein EAF6 homolog; hEAF6; Sarcoma antigen NY-SAR-91
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HAF1
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Expression Region
1-191aa
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AA Sequence
MAMHNKAAPP QIPDTRRELA ELVKRKQELA ETLANLERQI YAFEGSYLED TQMYGNIIRG WDRYLTNQKN SNSKNDRRNR KFKEAERLFS KSSVTSAAAV SALAGVQDQL IEKREPGSGT ESDTSPDFHN QENEPSQEDP EDLDGSVQGV KPQKAASSTS SGSHHSSHKK RKNKNRHRID LKLNKKPRAD Y
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Molecular Weight
48 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C1orf149, also known as "Chromosome 1 Open Reading Frame 149," is a relatively understudied protein that is gaining attention in molecular biology and biomedical research. Its gene is located on chromosome 1 and is thought to play roles in various cellular processes, though its specific functions are not yet fully elucidated. Preliminary studies suggest that C1orf149 may be involved in cell proliferation, differentiation, and apoptosis, which are crucial for maintaining normal cellular functions and tissue homeostasis. Furthermore, emerging evidence indicates that C1orf149 could be implicated in certain pathologies, including cancer, where its expression levels might be dysregulated. The exploration of C1orf149 through recombinant protein studies allows researchers to delve into its structure-function relationships and interactions with other cellular components. Utilizing techniques in protein expression and purification, researchers aim to characterize the protein's biochemical properties, assess its functional roles in cellular contexts, and identify potential interactions with other molecules. This research could provide insights into the molecular mechanisms underlying diseases associated with C1orf149 and may open avenues for developing novel therapeutic strategies. As more information becomes available, the characterization of C1orf149 and its recombinant protein could significantly enhance our understanding of its biological relevance and pave the way for future investigations in health and disease.
