Analytical Data
-
Gene name
C1orf146
- Application
-
Alternative Names
C1orf146; Uncharacterized Protein C1orf146
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q5VVC0
-
Expression Region
1-180aa
-
AA Sequence
MAESGKEKIK WTTTIIISSS LKSYEVATAL ENRSHKVRYS DSVENGSIIF SLSGVAFLLM DTKECLLSTE EIFLAKIEKF INIHQNSFLV LSAALHGPEE WKLMFRIQQR FLGCNLRILP VHNTVNAINL MCTIAKTTSK PYIDSICYRM ITAKAYIIEQ SPVWKTLQKI KLNSDSVNPN
-
Molecular Weight
46.8 KDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C1orf146, also known as the chromosome 1 open reading frame 146, is a gene located on chromosome 1 that has garnered interest in biomedical research due to its potential implications in various physiological and pathological processes. Recent studies suggest that C1orf146 may play a role in cellular functions such as proliferation, differentiation, and apoptosis, although its precise biological function remains largely elusive. Research into C1orf146 has been spurred by its observed expression patterns in several human tissues, particularly in cancer cells, where abnormalities in its expression may correlate with tumorigenesis and cancer progression. Moreover, initial investigations have indicated that C1orf146 may interact with key signaling pathways, hinting at its involvement in important cellular mechanisms. Given the lack of comprehensive functional characterization, the development of recombinant C1orf146 protein has become a focal point for researchers aiming to elucidate its specific roles and mechanisms of action. By producing and analyzing this protein, scientists hope to better understand the molecular underpinnings of diseases associated with C1orf146 dysregulation and explore its potential as a biomarker or therapeutic target in cancer and other disorders. As such, recombinant C1orf146 protein study not only addresses fundamental biological questions but also paves the way for potential clinical applications, making it a significant area of investigation within the fields of molecular biology and oncology.
