Analytical Data
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基因名
RAB3IL1
- Application
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别名
GRAB; Guanine nucleotide exchange factor for Rab 3A; Guanine nucleotide exchange factor for Rab-3A; Guanine nucleotide exchange factor for Rab3A; R3GEF_HUMAN; Rab-3A-interacting-like protein 1; Rab3A interacting like protein 1; RAB3A interacting protein (rabin3) like 1; Rab3A-interacting-like protein 1; RAB3IL1; Rabin3 like 1; Rabin3-like 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TBN0
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表达区间
1-382 aa
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氨基酸序列
MWSGPPQPDQ GLPPPLAAVP VPWKSTDPCQ GHRESPGALV ETSAGEEAQG QEGPAAAQLD VLRLRSSSME IREKGSEFLK EELHRAQKEL KLKDEECERL SKVREQLEQE LEELTASLFE EAHKMVREAN MKQAASEKQL KEARGKIDML QAEVTALKTL VITSTPASPN RELHPQLLSP TKAGPRKGHS RHKSTSSTLC PAVCPAAGHT LTPDREGKEV DTILFAEFQA WRESPTLDKT CPFLERVYRE DVGPCLDFTM QELSVLVRAA VEDNTLTIEP VASQTLPTVK VAEVDCSSTN TCALSGLTRT CRHRIRLGDS KSHYYISPSS RARITAVCNF FTYIRYIQQG LVRQDAEPMF WEIMRLRKEM SLAKLGFFPQ EA
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分子量
42.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB3IL1 (RAB3A interacting protein 1) is a member of the RAB protein family, which plays a crucial role in the regulation of intracellular trafficking and exocytosis. This protein has garnered attention in recent years due to its involvement in various cellular processes, such as neurotransmitter release and synaptic function. Abnormalities in RAB3IL1 expression have been linked to several neurological disorders, highlighting its potential as a biomarker and therapeutic target. Research has shown that RAB3IL1 interacts with RAB3A, influencing synaptic vesicle dynamics, thereby modulating neuronal communication. Understanding the structure and function of RAB3IL1 through recombinant protein studies can provide insights into its role in pathophysiological conditions. Moreover, the recombinant expression of RAB3IL1 allows for in vitro studies to explore its interaction with other proteins and its influence on cellular pathways. Such investigations are crucial for elucidating the molecular mechanisms underlying its function and the potential implications in disease states. As the understanding of RAB3IL1 continues to evolve, ongoing research aims to decode its complex biological roles and interaction networks, which may offer new avenues for therapeutic interventions in neurological diseases.
