Analytical Data
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Gene name
PTPRJ
- Application
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Alternative Names
CD 148; CD148; CD148 antigen; Density enhanced phosphatase 1; Density-enhanced phosphatase 1; DEP 1; DEP-1; HPTP eta; HPTPeta; Human density enhanced phosphatase 1; Protein tyrosine phosphatase eta; Protein tyrosine phosphatase receptor type J; Protein tyrosine phosphatase receptor type J polypeptide; Protein-tyrosine phosphatase eta; Protein-tyrosine phosphatase receptor type J; PTPJ; Ptprj; PTPRJ_HUMAN; R PTP Eta; R-PTP-eta; R-PTP-J; Receptor type tyrosine protein phosphatase eta; Receptor-type tyrosine-protein phosphatase eta; SCC 1; SCC1; susceptibility to colon cancer 1; mouse; homolog of
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q12913
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Expression Region
38-137 aa
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AA Sequence
GTPSPIPDPSVATVATGENGITQISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVIL
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Molecular Weight
36.74 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTPRJ, also known as protein tyrosine phosphatase receptor type J, is a member of the receptor-type protein tyrosine phosphatase (RPTP) family, which plays a critical role in cellular signaling pathways by dephosphorylating tyrosine residues on target proteins. Research on PTPRJ has gained significant attention due to its involvement in various physiological and pathological processes, including cell growth, differentiation, and immune responses. Dysregulation of PTPRJ has been linked to several diseases, particularly cancer and cardiovascular disorders, suggesting that it may serve as a potential therapeutic target. The study of recombinant PTPRJ proteins is pivotal for understanding their structural and functional aspects. By producing PTPRJ in a recombinant form, researchers can investigate its enzymatic activity, protein interactions, and regulatory mechanisms in a controlled environment. This knowledge could pave the way for the development of targeted therapies designed to modulate PTPRJ activity in disease contexts. Moreover, characterizing the recombinant protein allows for the exploration of its role in tyrosine phosphorylation dynamics and its influence on cellular signaling networks. Overall, the recombinant PTPRJ protein serves as a valuable tool for elucidating the biochemical basis of its function and its implications in health and disease.
