Analytical Data
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基因名
PTPDC1
- Application
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别名
PTPDC1; PTP9Q22; Protein tyrosine phosphatase domain-containing protein 1; EC 3.1.3.-
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A2A3K4
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表达区间
1-754 aa
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氨基酸序列
MAAGVLPQNE QPYSTLVNNS ECVANMKGNL ERPTPKYTKV GERLRHVIPG HMACSMACGG RACKYENPAR WSEQEQAIKG VYSSWVTDNI LAMARPSSEL LEKYHIIDQF LSHGIKTIIN LQRPGEHASC GNPLEQESGF TYLPEAFMEA GIYFYNFGWK DYGVASLTTI LDMVKVMTFA LQEGKVAIHC HAGLGRTGVL IACYLVFATR MTADQAIIFV RAKRPNSIQT RGQLLCVREF TQFLTPLRNI FSCCDPKAHA VTLPQYLIRQ RHLLHGYEAR LLKHVPKIIH LVCKLLLDLA ENRPVMMKDV SEGPGLSAEI EKTMSEMVTM QLDKELLRHD SDVSNPPNPT AVAADFDNRG MIFSNEQQFD PLWKRRNVEC LQPLTHLKRR LSYSDSDLKR AENLLEQGET PQTVPAQILV GHKPRQQKLI SHCYIPQSPE PDLHKEALVR STLSFWSQSK FGGLEGLKDN GSPIFHGRII PKEAQQSGAF SADVSGSHSP GEPVSPSFAN VHKDPNPAHQ QVSHCQCKTH GVGSPGSVRQ NSRTPRSPLD CGSSPKAQFL VEHETQDSKD LSEAASHSAL QSELSAEARR ILAAKALANL NESVEKEELK RKVEMWQKEL NSRDGAWERI CGERDPFILC SLMWSWVEQL KEPVITKEDV DMLVDRRADA AEALFLLEKG QHQTILCVLH CIVNLQTIPV DVEEAFLAHA IKAFTKVNFD SENGPTVYNT LKKIFKHTLE EKRKMTKDGP KPGL
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分子量
84.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTPDC1 (Protein Tyrosine Phosphatase Domain Containing 1) is a member of the protein tyrosine phosphatase (PTP) family, which plays a crucial role in cellular signaling by regulating phosphorylation states of proteins. Dysregulation of PTPs is linked to various diseases, including cancer, diabetes, and autoimmune disorders. The study of PTPDC1 has gained attention due to its potential involvement in key biological processes such as cell growth, differentiation, and apoptosis. Previous research indicates that PTPDC1 may have a role in the development of certain cancers, suggesting that it could be a potential therapeutic target. The recombinant expression of PTPDC1 allows for detailed analysis of its enzymatic activity and biological functions. By producing this protein in a controlled environment, researchers can investigate its structural properties, substrate specificity, and interactions with other proteins. Understanding the functional mechanisms of PTPDC1 may provide insights into its role in disease and identify novel strategies for intervention. As research continues to unveil the intricate pathways influenced by PTPDC1, the development of recombinant protein tools will aid in elucidating its physiological relevance and therapeutic potential.
