Analytical Data
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基因名
STX10
- Application
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别名
STX10；SYN10；Syntaxin-10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60499
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表达区间
2-228aa
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氨基酸序列
SLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQ
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分子量
41.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STX10, or Syntaxin 10, is a member of the syntaxin family of proteins that play a crucial role in the regulation of intracellular membrane trafficking and exocytosis. It is primarily involved in the fusion of vesicles with membranes, a key process for neurotransmitter release, hormone secretion, and various cellular communication mechanisms. Research on STX10 has gained prominence due to its implications in neurobiology and its potential link to various neurological disorders. Mutations in the STX10 gene have been associated with conditions such as mental retardation and other cognitive impairments, suggesting that understanding the function and regulation of STX10 could provide insights into the molecular basis of these disorders. Additionally, STX10's role in immune response and its interaction with various partner proteins make it a significant target for studying synaptic functions and neurodegenerative diseases. The development of recombinant STX10 protein has facilitated detailed biochemical studies, allowing for the exploration of its structure, function, and interactions, thereby contributing to our understanding of cellular mechanisms and potential therapeutic approaches for related pathologies. Overall, the study of STX10 is important for elucidating the complexities of membrane dynamics and their impact on health and disease.
