Analytical Data
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Gene name
PTOV1
- Application
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Alternative Names
PTOV1; ACID2; PP642; UNQ6127/PRO20092; Prostate tumor-overexpressed gene 1 protein; PTOV-1; Activator interaction domain-containing protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86YD1
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Expression Region
1-416 aa
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AA Sequence
MVRPRRAPYR SGAGGPLGGR GRPPRPLVVR AVRSRSWPAS PRGPQPPRIR ARSAPPMEGA RVFGALGPIG PSSPGLTLGG LAVSEHRLSN KLLAWSGVLE WQEKRRPYSD STAKLKRTLP CQAYVNQGEN LETDQWPQKL IMQLIPQQLL TTLGPLFRNS QLAQFHFTNR DCDSLKGLCR IMGNGFAGCM LFPHISPCEV RVLMLLYSSK KKIFMGLIPY DQSGFVSAIR QVITTRKQAV GPGGVNSGPV QIVNNKFLAW SGVMEWQEPR PEPNSRSKRW LPSHVYVNQG EILRTEQWPR KLYMQLIPQQ LLTTLVPLFR NSRLVQFHFT KDLETLKSLC RIMDNGFAGC VHFSYKASCE IRVLMLLYSS EKKIFIGLIP HDQGNFVNGI RRVIANQQQV LQRNLEQEQQ QRGMGG
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Molecular Weight
46.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTOV1 (Prostate Tumor Overexpressed 1) is a protein that has garnered significant interest in cancer research, particularly in the context of prostate cancer. It is often found to be overexpressed in prostate tumor tissues, suggesting a potential role in tumorigenesis and cancer progression. Researchers have been investigating the molecular function of PTOV1, as its overexpression is associated with aggressive tumor characteristics and poor patient prognosis. The protein is thought to participate in critical cellular processes such as proliferation, apoptosis, and metastasis, making it a potential biomarker for cancer diagnosis and a target for therapeutic intervention. Studies have shown that the regulation of PTOV1 expression may influence cancer cell behavior, further highlighting its significance in oncological research. Furthermore, the exploration of PTOV1 as a reprogrammed protein could pave the way for the development of new treatment strategies that aim to inhibit its function, thereby hindering tumor growth and improving treatment outcomes for patients with prostate cancer. Overall, the ongoing research into PTOV1 is crucial for understanding its role in cancer biology and its potential implications for developing targeted therapies.
