Analytical Data
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Gene name
GALNT7
- Application
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Alternative Names
GALNT7；N-acetylgalactosaminyltransferase 7
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86SF2
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Expression Region
30-657aa
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AA Sequence
PRPDDPSPLSRMREDRDVNDPMPNRGGNGLAPGEDRFKPVVPWPHVEGVE VDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTFTYHDPVLRP GILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVA SDMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHS VIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREG LIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTVPL IDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRKTKT EPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGK LLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDY FYASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPP KNVDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQL MQYDQCLTKGADGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSGKCLDRS EVLHQVFISNCDSSKTTQKWEMNNIHSVVDHHHHHH
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Molecular Weight
73 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GALNT7, a member of the glycosyltransferase family, plays a crucial role in the biosynthesis of mucin-type O-glycans. These glycans are essential for various biological processes, including cell signaling, adhesion, and immune response. Recent studies have highlighted the significance of GALNT7 in various diseases, including cancer, where it has been implicated in tumor progression and metastasis. The enzyme catalyzes the first step in the O-glycosylation process by transferring N-acetylgalactosamine (GalNAc) to serine or threonine residues on target proteins. Understanding the structural and functional characteristics of GALNT7 has become increasingly important for elucidating its role in health and disease. Recombinant GALNT7 protein production has emerged as a vital approach to investigate its enzymatic activity, substrate specificity, and interaction with other cellular components. The characterization of GALNT7 through recombinant technology not only enhances our understanding of O-glycosylation mechanisms but also opens avenues for potential therapeutic applications, particularly in targeting glycosylation patterns in cancer treatment. As researchers continue to explore the complexities of glycosylation, GALNT7 stands out as a key enzyme that could provide insights into novel biomarker development and drug design, emphasizing the need for continued investigation into its biology and clinical significance.
