Analytical Data
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Gene name
C16orf53
- Application
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Alternative Names
C16orf53; Chromosome 16 open reading frame 53; FLJ22459; GAS; Glutamate rich coactivator interacting with SRC1/NCOA1; MGC4606; Pa1; PA1_HUMAN; PAXIP1 associated Protein 1; PAXIP1-associated Protein 1; PTIP associated 1 Protein; PTIP associated Protein 1; PTIP-associated Protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BTK6
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Expression Region
1-254aa
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AA Sequence
MSLARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPLRSSGSSLFPRQRKY
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Molecular Weight
54.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C16orf53, also known as chromosome 16 open reading frame 53, is a protein-coding gene that has gained attention in biological and medical research due to its potential roles in various cellular processes and implications in human diseases. Initially characterized as a gene of unknown function, studies have suggested that C16orf53 may be involved in key biological pathways, including cell proliferation, apoptosis, and stress response. The exploration of C16orf53's functions has become increasingly relevant, particularly in the context of cancer research, where its expression levels may correlate with tumor progression and patient prognosis. Recombination studies of the C16orf53 protein have been undertaken to elucidate its structure-function relationships, leading to insights into its molecular mechanisms. These studies typically involve the expression of the C16orf53 gene in various host systems to produce recombinant proteins for functional assays, structural analyses, and interaction studies. Understanding the role of C16orf53 in cellular contexts may provide valuable information for developing therapeutic strategies and biomarkers for diseases, particularly malignancies. Additionally, the insights gained from these studies could pave the way for further investigations into the gene's regulatory mechanisms and its potential involvement in other physiological and pathological processes, ultimately contributing to the field of molecular biology and medicine.











