Analytical Data
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基因名
RAB8A
- Application
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别名
RAB8A；MEL；RAB8；Ras-related Protein Rab-8A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P61006
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表达区间
6-176aa
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氨基酸序列
DYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKK
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分子量
19.49 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
RAB8A is a member of the RAB family of small GTPases, which play critical roles in regulating intracellular transport and membrane trafficking. It is primarily involved in the transport of vesicles, influencing processes like exocytosis and endocytosis. Dysregulation of RAB8A has been implicated in various pathological conditions, including cancer, neurodegenerative diseases, and developmental disorders. Research on RAB8A recombinant proteins has gained momentum due to their potential therapeutic relevance. Scientists are increasingly focused on characterizing its functional domains, understanding its interaction with effector proteins, and revealing its role in cellular processes. The production of RAB8A recombinant protein allows for in-depth studies of its biochemical properties and molecular mechanisms. Through these studies, researchers aim to uncover novel therapeutic targets and pathways, ultimately paving the way for new treatments that leverage the manipulation of RAB8A activity. Understanding the structure-function relationship of RAB8A through recombinant expression systems offers invaluable insights into its role in health and disease, making it a promising target for future biomedical research.
