Cat: PA1000-5121

Recombinant Human CTF1 Protein,His

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Analytical Data

  • Gene name

    CTF1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CTF1;Cardiotrophin-1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q16619

  • Expression Region

    1-201aa

  • AA Sequence

    MSRREGSLED PQTDSSVSLL PHLEAKIRQT HSLAHLLTKY AEQLLQEYVQ LQGDPFGLPS FSPPRLPVAG LSAPAPSHAG LPVHERLRLD AAALAALPPL LDAVCRRQAE LNPRAPRLLR RLEDAARQAR ALGAAVEALL AALGAANRGP RAEPPAATAS AASATGVFPA KVLGLRVCGL YREWLSRTEG DLGQLLPGGS A

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CTF1, or Cell Cycle and Transcription Factor 1, is a crucial protein involved in the regulation of transcription and cell cycle progression. Its role has garnered significant attention due to its implications in cellular functions and potential links to various diseases, including cancer. Research indicates that CTF1 may play a pivotal role in the regulation of gene expression during different cellular states, influencing processes such as proliferation and differentiation. Understanding the structure and function of CTF1 is essential for elucidating its mechanism of action and its interactions with other cellular factors. Advances in recombinant protein technology, particularly in heterologous expression systems, have facilitated the production and characterization of CTF1. This has allowed researchers to explore the protein's biochemical properties and its functional roles in detail. By investigating the post-translational modifications and structural dynamics of CTF1, scientists aim to uncover its specific pathways in disease pathology and potential therapeutic angles. Given the importance of transcription factors in cellular regulation, CTF1 presents an intriguing target for both basic research and drug development, making it a focal point of study in molecular biology and oncology.

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