Analytical Data
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Gene name
RTBDN
- Application
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Alternative Names
RTBDN；Retbindin
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BSG5
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Expression Region
31-229aa
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AA Sequence
SRPLQARSQQHHGLAADLGKGKLHLAGPCCPSEMDTTETSGPGNHPERCG VPSPECESFLEHLQR ALRSRFRLRLLGVRQAQPLCEELCQAWFANCEDDITCGPTWLPLSEKRGC EPSCLTYGQTFADGT DLCRSALGHALPVAAPGARHCFNISISAVPRPRPGRRGREAPSRRSRSPR TSILDAAGSGSGSGS GSGPVDHHHHHH
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Molecular Weight
22 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RTBDN (Regulator of Transcription and DNA Damage Response), a protein implicated in various cellular processes, has garnered significant attention in recent years due to its roles in regulating transcription and responding to DNA damage. As a crucial player in maintaining genomic stability, RTBDN is believed to facilitate the orchestration of molecular pathways that govern cell cycle progression, DNA repair mechanisms, and gene expression. Dysregulation of RTBDN has been associated with several diseases, including cancer, where it may contribute to aberrant cell proliferation and survival. Research has increasingly focused on elucidating the mechanistic functions of RTBDN and its interactions with other proteins involved in the DNA damage response. Understanding RTBDN's structure-function relationship and its regulatory mechanisms could pave the way for novel therapeutic strategies targeting its pathways, particularly in cancer treatment. Furthermore, studies utilizing recombinant RTBDN allow for the exploration of its biochemical properties, interaction networks, and functional domains in a controlled setting, providing vital insights into its contribution to cellular homeostasis and disease pathology. As research progresses, unraveling the complexities of RTBDN will be essential for developing targeted interventions that can enhance the body's ability to manage DNA damage and improve therapeutic outcomes for patients with related disorders.
