Analytical Data
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Gene name
Reg3γ
- Application
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96PJ0
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Expression Region
全长
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AA Sequence
full
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Reg3γ, also known as regenerating islet-derived protein 3 gamma, is a crucial member of the Reg family of proteins, which are initially characterized for their role in pancreatic regeneration. These proteins exhibit antimicrobial and immunomodulatory properties, making them significant in the context of gut health and inflammation. Recent studies have highlighted the role of Reg3γ in various physiological and pathological conditions, particularly in the gut, where it serves as a key effector in the innate immune response against bacterial infections. The regulation of Reg3γ expression is tightly controlled by cytokines such as IL-22 and can be influenced by gut microbiota, emphasizing its role as a mediator of the host-microbe interaction. Moreover, Reg3γ shows promise in influencing tumor microenvironments and is being investigated for its potential role in cancer biology, particularly in gastrointestinal tumors. Understanding the mechanisms underlying Reg3γ function and regulation can provide valuable insights into its therapeutic applications for inflammatory diseases and cancer, making it a focal point of research in immunology and regenerative medicine. The recombinant form of Reg3γ is being explored for its potential use in biotherapeutic strategies, harnessing its unique properties to enhance mucosal immunity and support tissue repair. Through these investigations, Reg3γ is emerging as a multifunctional protein with significant implications for improving human health and combating disease.
