Analytical Data
-
基因名
BTN3A2
- Application
-
别名
BTN3A2；BT3.2；BTF3；BTF4；Butyrophilin subfamily 3 member A2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P78410
-
表达区间
30-248aa
-
氨基酸序列
QFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVY ADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQ DGDFYEKALVELKVAALGSNLHVEVKGYEDGGIHLECRSTGWYPQPQIQW SNAKGENIPAVEAPVVADGVGLYEVAASVIMRGGSGEGVSCIIRNSLLGL EKTASISIADPFFRSAQPWVDHHHHHH
-
分子量
25 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BTN3A2, a member of the butyrophilin family, plays a crucial role in immune regulation and T cell activation. It is primarily expressed in antigen-presenting cells and has been implicated in the recognition of non-peptide antigens by γδ T cells, which are essential components of the immune system. Research has shown that BTN3A2 interacts with the Vγ9Vδ2 T cell receptor, stimulating these T cells to respond to various pathogens and tumors. Given its pivotal role in immune responses, BTN3A2 has garnered attention in cancer immunotherapy and infectious disease research. Recombinant BTN3A2 protein studies aim to elucidate its structure-function relationship, binding characteristics, and the mechanisms through which it activates γδ T cells. Investigating BTN3A2's properties may lead to novel strategies that harness the immune system to target malignancies or enhance responses to infections. Additionally, understanding BTN3A2's interactions with other immune components can provide insights into regulatory pathways that govern immune surveillance and tolerance, ultimately advancing therapeutic approaches in immunology.
