Cat: PA1000-4943

Recombinant Human ITIH3 Protein,His

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Analytical Data

  • Gene name

    ITIH3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ITIH3;Inter-alpha-trypsin inhibitor heavy chain H3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q06033

  • Expression Region

    35-651aa

  • AA Sequence

    LPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELP KTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRK LEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEI EVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQR SCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKN VAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKE HLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPE RSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYN FLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAI LDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEV DMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTAR ALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEDAEATPVSPAMSY LTSYQPPQNPYYYVDGDVDHHHHHH

  • Molecular Weight

    70 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ITIH3 (Inter-alpha-trypsin inhibitor heavy chain 3) is a member of the inter-alpha-trypsin inhibitor family, primarily known for its role in modulating the immune response and promoting tissue repair. Recent studies have highlighted its involvement in various pathological conditions, including inflammation, cancer, and cardiovascular diseases. The interaction of ITIH3 with hyaluronic acid and other extracellular matrix components suggests its potential role in cell signaling and matrix stability. This has fueled interest in its therapeutic applications, particularly in regenerative medicine and as a biomarker for disease. Furthermore, advances in recombinant protein technology enable the production of ITIH3 for detailed functional studies, allowing researchers to explore its mechanisms of action and interactions within the biological system. Understanding the structural and functional properties of ITIH3 can lead to novel treatments and diagnostic tools, making it a significant focus in biomedical research.

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