Cat: PA1000-4923

Recombinant Human PSG3 Protein,His

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Analytical Data

  • Gene name

    PSG3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    PSG3;Pregnancy-specific beta-1-glycoProtein 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q16557

  • Expression Region

    35-428aa

  • AA Sequence

    QVTIEA EPTKVSKGKD VLLLVHNLPQ NLAGYIWYKG QMKDLYHYIT SYVVDGQIII YGPAYSGRET VYSNASLLIQ NVTREDAGSY TLHIVKRGDG TRGETGHFTF TLYLETPKPS ISSSNLYPRE DMEAVSLTCD PETPDASYLW WMNGQSLPMT HSLQLSKNKR TLFLFGVTKY TAGPYECEIR NPVSASRSDP VTLNLLPKLP KPYITINNLN PRENKDVLAF TCEPKSENYT YIWWLNGQSL PVSPRVKRPI ENRILILPSV TRNETGPYQC EIQDRYGGIR SYPVTLNVLY GPDLPRIYPS FTYYHSGENL YLSCFADSNP PAEYSWTING KFQLSGQKLF IPQITTKHSG LYACSVRNSA TGMESSKSMT VKVSAPSGTG HLPGLNPL

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

PSG3, or Pregnancy-Specific Glycoprotein 3, is a member of the pregnancy-specific glycoprotein family, which plays essential roles in various physiological processes during pregnancy. This family of proteins is predominantly produced by trophoblast cells and is secreted into maternal circulation, where its levels can influence maternal-fetal interactions and immune modulation. Research on PSG3 has gained attention due to its potential implications in pregnancy-related disorders and its involvement in the regulation of immune responses at the maternal-fetal interface. Elevated or aberrant levels of PSG3 have been associated with conditions such as preeclampsia, recurrent pregnancy loss, and intrauterine growth restriction, making it a critical biomarker for monitoring pregnancy health. Furthermore, studies have explored the potential role of PSG3 in promoting trophoblast invasion and survival, which are crucial for successful implantation and placental development. Understanding the functional mechanisms of PSG3 could offer insights into its contributions to pregnancy maintenance and the pathophysiology of pregnancy complications. This underscores the importance of ongoing research into PSG3, aiming to elucidate its molecular functions and potential therapeutic applications for improving pregnancy outcomes and addressing maternal-fetal health challenges.

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