Cat: PA2000-2090

Recombinant E.coli RIHB Protein,His

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Analytical Data

  • Gene name

    RIHB

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RIHB;yeiK;Pyrimidine-specific ribonucleoside hydrolase RihB

  • Species

    E.coli

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P33022

  • Expression Region

    1-313aa

  • AA Sequence

    MEKRKIILDC DPGHDDAIAI MMAAKHPAID LLGITIVAGN QTLDKTLING LNVCQKLEIN VPVYAGMPQP IMRQQIVADN IHGETGLDGP VFEPLTRQAE STHAVKYIID TLMASDGDIT LVPVGPLSNI AVAMRMQPAI LPKIREIVLM GGAYGTGNFT PSAEFNIFAD PEAARVVFTS GVPLVMMGLD LTNQTVCTPD VIARMERAGG PAGELFSDIM NFTLKTQFEN YGLAGGPVHD ATCIGYLINP DGIKTQEMYV EVDVNSGPCY GRTVCDELGV LGKPANTKVG ITIDTDWFWG LVEECVRGYI KTH

  • Molecular Weight

    33.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

RIHB, or Recombinant Interleukin-1β Homolog, is a synthetic protein that has garnered attention in the field of immunology and biopharmaceutical research due to its potential therapeutic applications. Interleukin-1β (IL-1β) is a crucial cytokine involved in the inflammatory response, and its dysregulation is associated with various diseases, including autoimmune disorders, inflammatory diseases, and certain cancers. The recombinant form of this protein, RIHB, allows for comprehensive studies on its structure-function relationships and biological activities, facilitating the understanding of its mechanism in immune system modulation. Advances in recombinant DNA technology have enabled the precise manipulation and expression of RIHB in various biological systems, thus supporting investigations into its roles in cell signaling pathways and its interactions with other immune components. Additionally, RIHB can serve as a valuable tool in drug development, offering insights into novel therapeutic strategies for diseases characterized by chronic inflammation. The growing body of research surrounding RIHB underscores its significance in both basic and applied sciences, aiming to elucidate its therapeutic potential and pave the way for innovative treatments that can better manage inflammatory and autoimmune conditions.

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