Analytical Data
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基因名
IL2RB
- Application
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别名
IL2RB；IL15RB；Interleukin-2 receptor subunit beta
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P14784
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表达区间
27-239aa
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氨基酸序列
AVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCEL LPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKP FENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGH TWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQP LAFRTKPAALGKD
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分子量
25 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of IL2RB (Interleukin 2 Receptor Beta) recombinant protein is rooted in the exploration of immune system regulation and its implications for various diseases, including cancer and autoimmune disorders. IL2RB is a critical component of the interleukin-2 receptor complex, which plays a pivotal role in T cell proliferation, survival, and differentiation. Dysregulation of this pathway can lead to impaired immune responses or uncontrolled proliferation of T cells, contributing to disease pathogenesis. Researchers have focused on producing recombinant IL2RB to investigate its structure-function relationship, biochemical properties, and potential therapeutic applications. By utilizing recombinant DNA technology, scientists can express high quantities of IL2RB, enabling detailed studies of its interactions with ligands and other receptors. Furthermore, recombinant IL2RB serves as a valuable tool for developing targeted therapies, particularly in cancer immunotherapy, where modulating T cell responses can enhance therapeutic efficacy. Additionally, understanding the molecular mechanisms underlying IL2RB's role in immune regulation may lead to innovative treatment strategies for immunological diseases. Thus, the research on IL2RB recombinant protein is crucial for advancing our knowledge of immune system dynamics and developing next-generation immunotherapeutics.
