Cat: PA1000-4758

Recombinant Human PNLIPRP1 Protein,His

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Analytical Data

  • Gene name

    PNLIPRP1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    PNLIPRP1;PLRP1;Inactive pancreatic lipase-related Protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P54315

  • Expression Region

    1-467aa

  • AA Sequence

    MLIFWTITLF LLGAAKGKEV CYEDLGCFSD TEPWGGTAIR PLKILPWSPE KIGTRFLLYT NENPNNFQI LLLSDPSTIE ASNFQMDRKT RFIIHGFIDK GDESWVTDMC KKLFEVEEVN CICVDWKKG SQATYTQAAN NVRVVGAQVA QMLDILLTEY SYPPSKVHLI GHSLGAHVAG EAGSKTPGL SRITGLDPVE ASFESTPEEV RLDPSDADFV DVIHTDAAPL IPFLGFGTNQ QMGHLDFFP NGGESMPGCK KNALSQIVDL DGIWAGTRDF VACNHLRSYK YYLESILNPD GFAAYPCTS YKSFESDKCF PCPDQGCPQM GHYADKFAGR TSEEQQKFFL NTGEASNFAR WRYGVSITL SGRTATGQIK VALFGNKGNT HQYSIFRGIL KPGSTHSYEF DAKLDVGTIE KVKFLWNNN VINPTLPKVG ATKITVQKGE EKTVYNFCSE DTVREDTLLT LTPC

  • Molecular Weight

    51 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

PNLIPRP1 (pancreatic lipase-related protein 1) is a member of the pancreatic lipase gene family, primarily expressed in the pancreas, and plays a critical role in lipid metabolism. Its study has gained attention due to its potential implications in various metabolic disorders, including obesity and type 2 diabetes. Recent research has highlighted PNLIPRP1's involvement in triglyceride hydrolysis and its regulatory effects on energy homeostasis. Understanding the structure and function of PNLIPRP1 can provide insights into its enzymatic mechanisms and the physiological processes of fat digestion. Additionally, recombinant PNLIPRP1 proteins have been utilized for biochemical assays and pharmacological studies, aiding in the development of therapeutic strategies targeting lipid-related diseases. As dysfunctions in lipid metabolism are associated with numerous health issues, investigating PNLIPRP1 through recombinant expression offers valuable opportunities for advancing our knowledge in metabolic research and potential clinical applications.

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