Analytical Data
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基因名
PACSIN2
- Application
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别名
PACSIN2；Protein kinase C and casein kinase substrate in neurons Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UNF0
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表达区间
1-486aa
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氨基酸序列
MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT EWARRWRQLV EKGPQYGTVE KAWMAFMSEA ERVSELHLEV KASLMNDDFE KIKNWQKEAF HKQMMGGFKE TKEAEDGFRK AQKPWAKKLK EVEAAKKAHH AACKEEKLAI SREANSKADP SLNPEQLKKL QDKIEKCKQD VLKTKEKYEK SLKELDQGTP QYMENMEQVF EQCQQFEEKR LRFFREVLLE VQKHLDLSNV AGYKAIYHDL EQSIRAADAV EDLRWFRANH GPGMAMNWPQ FEEWSADLNR TLSRREKKKA TDGVTLTGIN QTGDQSLPSK PSSTLNVPSN PAQSAQSQSS YNPFEDEDDT GSTVSEKDDT KAKNVSSYEK TQSYPTDWSD DESNNPFSST DANGDSNPFD DDATSGTEVR VRALYDYEGQ EHDELSFKAG DELTKMEDED EQGWCKGRLD NGQVGLYPAN YVEAIQ
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PACSIN2, a member of the PACSIN family of proteins, plays a critical role in various cellular processes, including endocytosis, membrane trafficking, and cytoskeletal dynamics. Emerging research has highlighted the significance of PACSIN2 in neural development, synaptic function, and cellular signaling pathways, suggesting its potential implications in neurodegenerative diseases and cancer. The protein’s ability to interact with actin filaments and other signaling molecules positions it as a pivotal player in maintaining cellular architecture and functionality. Recent advances in recombinant protein technology have facilitated the generation of PACSIN2 in its active form, allowing for detailed studies into its structural and functional properties. Researchers have employed techniques such as X-ray crystallography and cryo-electron microscopy to elucidate its three-dimensional structure, providing insights into its interaction domains and mechanisms of action. Investigating PACSIN2's recombinant form not only enhances our understanding of its biological roles but also opens avenues for potential therapeutic interventions targeting its associated pathways. As such, PACSIN2 serves as a promising candidate for future research focused on cellular mechanics and disease pathology, demonstrating the importance of recombinant protein studies in unraveling complex biological systems.
