Analytical Data
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基因名
HNRNPH1
- Application
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别名
HNRNPH1；HNRPH；HNRPH1；Heterogeneous nuclear ribonucleoProtein H
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P31943
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表达区间
2-216aa
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氨基酸序列
MLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAG
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分子量
51.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HNRNPH1, known as heterogeneous nuclear ribonucleoprotein H1, is a crucial RNA-binding protein that plays a significant role in post-transcriptional gene regulation, mRNA processing, and stability. It is involved in diverse cellular processes, including splicing, transport, and translation of RNA, making it vital for normal cellular function and development. Dysregulation of HNRNPH1 has been implicated in various diseases, including cancer and neurological disorders, emphasizing the need for in-depth understanding of its molecular mechanisms. The study of recombinant HNRNPH1 protein facilitates the investigation of its structure-function relationships and interaction with RNA and other cellular components. By producing and characterizing HNRNPH1 recombinant protein, researchers can elucidate its role in RNA metabolism and the pathogenesis of related diseases. This research is particularly relevant in the context of developing therapeutic strategies targeting HNRNPH1 and its pathways, with the potential for advancements in precision medicine. The advancements in recombinant protein techniques also open avenues for high-throughput screening of small molecules that may modulate HNRNPH1 function, further enriching our understanding of its biological significance and therapeutic potential.
