Analytical Data
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基因名
PACSIN1
- Application
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别名
PACSIN1；KIAA1379；Protein kinase C and casein kinase substrate in neurons Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BY11
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表达区间
1-444aa
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氨基酸序列
MSSSYDEASL APEETTDSFW EVGNYKRTVK RIDDGHRLCN DLMNCVQERA KIEKAYGQQL TDWAKRWRQL IEKGPQYGSL ERAWGAIMTE ADKVSELHQE VKNNLLNEDL EKVKNWQKDA YHKQIMGGFK ETKEAEDGFR KAQKPWAKKM KELEAAKKAY HLACKEEKLA MTREMNSKTE QSVTPEQQKK LQDKVDKCKQ DVQKTQEKYE KVLEDVGKTT PQYMENMEQV FEQCQQFEEK RLVFLKEVLL DIKRHLNLAE NSSYIHVYRE LEQAIRGADA QEDLRWFRST SGPGMPMNWP QFEEWNPDLP HTTTKKEKQP KKAEGVALTN ATGAVESTSQ AGDRGSVSSY DRGQPYATEW SDDESGNPFG GSETNGGANP FEDDSKGVRV RALYDYDGQE QDELSFKAGD ELTKLGEEDE QGWCRGRLDS GQLGLYPANY VEAI
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PACSIN1, a member of the PACSIN (Protein Kinase C and Casein Kinase Substrate in Neurons) family, plays a critical role in various cellular processes, including endocytosis, cytoskeleton organization, and cell signaling. Initially identified for its involvement in neuronal development and synaptic functions, PACSIN1 has recently garnered attention in the context of various diseases, including cancer and neurodegenerative disorders. The protein functions as a scaffolding molecule, facilitating the interaction between different signaling pathways and cytoskeletal elements, which is essential for maintaining cellular integrity and function. Current research focuses on characterizing PACSIN1's structural properties, interactions with other proteins, and its regulatory mechanisms. Moreover, understanding the role of PACSIN1 in pathological conditions may uncover new therapeutic targets and strategies. Recombinant PACSIN1 protein is crucial for these studies, as it allows researchers to investigate its biochemical properties and interactions in vitro, providing insights into its physiological roles and potential implications in disease. The production of PACSIN1 as a recombinant protein is therefore essential for advancing our knowledge of its function and relevance in both normal cellular physiology and disease pathology.
