Cat: PA1000-4683

Recombinant Human CEACAM8 Protein,His

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Analytical Data

  • Gene name

    CEACAM8

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CEACAM8;CGM6;Carcinoembryonic antigen-related cell adhesion molecule 8

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P31997

  • Expression Region

    1-319aa

  • AA Sequence

    MGPISAPSCR WRIPWQGLLL TASLFTFWNP PTTAQLTIEA VPSNAAEGKE VLLLVHNLPQ DPRGYNWYKG ETVDANRRII GYVISNQQIT PGPAYSNRET IYPNASLLMR NVTRNDTGSY TLQVIKLNLM SEEVTGQFSV HPETPKPSIS SNNSNPVEDK DAVAFTCEPE TQNTTYLWWV NGQSLPVSPR LQLSNGNRTL TLLSVTRNDV GPYECEIQNP ASANFSDPVT LNVLYGPDAP TISPSDTYYH AGVNLNLSCH AASNPPSQYS WSVNGTFQQY TQKLFIPNIT TKNSGSYACH TTNSATGRNR TTVRMITVS

  • Molecular Weight

    33 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

CEACAM8, or Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8, is a member of the CEACAM family, which plays a significant role in immune responses and cell adhesion processes. Research into CEACAM8 has gained attention due to its involvement in various physiological and pathological conditions, particularly in the context of inflammatory diseases and certain types of cancer. CEACAM8 is primarily expressed on neutrophils and has been implicated in the regulation of neutrophil activation and migration, making it a potential biomarker for infections and inflammatory states. Furthermore, its interactions with other CEACAM family members and pathogens suggest a complex role in host defense mechanisms. The development of recombinant CEACAM8 provides a valuable tool for studying its functional properties, exploring its role in leukocyte biology, and evaluating its potential as a therapeutic target or diagnostic marker. Characterizing this protein can enhance our understanding of immune system dynamics and contribute to the advancement of targeted therapies for diseases where CEACAM8 is a key player. As such, recombinant CEACAM8 is vital for elucidating its biological roles and paving the way for innovative clinical applications.

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