Analytical Data
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基因名
FXYD2
- Application
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别名
FXYD2;ATP1C;ATP1G1;Sodium/potassium-transporting ATPase subunit gamma
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P54710
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表达区间
1-64aa
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氨基酸序列
MDRWYLGGSPKGDVDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQINEDEP
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分子量
34.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FXYD2 is a member of the FXYD protein family, which plays a critical role in modulating ion transport in epithelial cells. Specifically, FXYD2 is known to interact with the Na+/K+ ATPase, affecting its activity and function, which is essential for maintaining cellular ion homeostasis. The expression of FXYD2 is found to be regulated in various physiological and pathological conditions, including cardiac and renal functions. Research has indicated that alterations in FXYD2 expression correlate with several diseases, such as hypertension and heart failure, thus highlighting its potential as a biomarker for these conditions. Recombinant FXYD2 protein is therefore of considerable interest for studying its structure-function relationships and identifying the molecular mechanisms underlying its role in ion transport and cellular signaling pathways. The recombinant form allows researchers to investigate its biophysical properties, interactions with other membrane proteins, and its impact on ion pump activity in a controlled environment. Understanding FXYD2 through recombinant protein studies can contribute to elucidating its biological significance and may offer insights into therapeutic targets for related disorders. As research progresses, the development and application of FXYD2 recombinant protein could pave the way for novel interventions in diseases associated with disrupted ion transport.












