Analytical Data
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基因名
SULT4A1
- Application
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别名
SULT4A1；SULTX3；Sulfotransferase 4A1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BR01
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表达区间
1-284aa
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氨基酸序列
MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWI VTYPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIK ELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLR TMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDMH RDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCSAEALPVGRGRV GLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL
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分子量
33 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SULT4A1 (sulfotransferase family 4, member A1) is a member of the sulfotransferase enzyme family that plays a crucial role in the sulfation of various substrates, including neurotransmitters, steroids, and xenobiotics. It is unique among sulfotransferases due to its widespread distribution in the human brain, where it is implicated in modulating the activity of neurotransmitters and potentially influencing cognitive functions and neuropsychiatric disorders. Recent research has highlighted the importance of SULT4A1 in detoxification processes, as it participates in the metabolic inactivation of endogenous and exogenous compounds, thereby contributing to maintaining cellular homeostasis. Additionally, variations in the expression and activity of SULT4A1 have been correlated with susceptibility to neurological diseases, making it a target of interest for studying disease mechanisms and developing therapeutic interventions. Furthermore, the production of recombinant SULT4A1 protein enables detailed biochemical assays, structural studies, and the investigation of its role in sulfation pathways, paving the way for advances in pharmacology and toxicology. Understanding the function and regulation of SULT4A1 is crucial for elucidating its physiological significance and therapeutic potential.
