Analytical Data
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Gene name
C21orf2
- Application
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Alternative Names
C21orf2；C21orf2；LRRC76；Cilia- and flagella-associated Protein 410
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43822
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Expression Region
1-375aa
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AA Sequence
MKLTRKMVLTRAKASELHSVRKLNCWGSRLTDISICQEMPSLEVITLSVN SISTLEPVSRCQRLSELYLRRNRIPSLAELFYLKGLPRLRVLWLAENPCC GTSPHRYRMTVLRTLPRLQKLDNQAVTEEELSRALSEGEEITAAPEREGT GHGGPKLCCTLSSLSSAAETGRDPLDSEEEATGAQDERGLKPPSRGQFPS LSARDASSSHRGRVSGGPLGAAAASAHCTHCTETVGREHGASQGPVGREH GASQGLEELCPRGSCVCGSVNAHTRVTRAPHGAVLAPQPLLLSWSVECGP GPCWAEGNRSHVEEVPHTRPQAGLLCSDSPSVPNVLTAILLLLRELDAEG LEAVQQTVGSRLQALRGEEVQEHAE
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Molecular Weight
40 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C21orf2, also known as chromosome 21 open reading frame 2, is a gene located on human chromosome 21 that has garnered attention due to its potential involvement in various cellular processes and diseases, particularly in the context of Down syndrome, which is caused by an extra copy of chromosome 21. Recent studies have indicated that C21orf2 may play a role in cellular signaling, metabolism, and possibly the regulation of gene expression. The protein encoded by C21orf2 remains largely uncharacterized, and understanding its structure and function is crucial for elucidating its biological role. Researchers have begun to produce recombinant C21orf2 protein to investigate its properties, interactions, and functional implications in cellular systems. The availability of this recombinant protein enables more detailed biochemical assays, structural studies, and functional analyses. Moreover, insights gained from C21orf2 research may contribute to a deeper understanding of Down syndrome pathology, offering avenues for therapeutic intervention. Overall, the study of recombinant C21orf2 protein is positioned at the intersection of genetic research, molecular biology, and potential clinical applications, making it a significant focus in contemporary biomedical research.
