Analytical Data
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基因名
CRISP3
- Application
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别名
CRISP3;;Cysteine-rich secretory Protein 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P54108
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表达区间
21-245aa
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氨基酸序列
NEDKDPAFTALLTTQTQVQREIVNKHNELRRAVSPPARNMLKMEWNKEAA ANAQKWANQCNYRHSNPKDRMTSLKCGENLYMSSASSSWSQAIQSWFDEY NDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYYYVCQ YCPAGNWANRLYVPYEQGAPCASCPDNCDDGLCTNGCKYEDLYSNCKSLK LTLTCKHQLVRDSCKASCNCSNSIYVDHHHHHH
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分子量
27 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CRISP3, a member of the cysteine-rich secretory protein (CRISP) family, has garnered attention due to its potential role in various physiological and pathological processes. Initially identified in the context of reproductive biology, CRISP3 is predominantly expressed in the male reproductive tract, particularly in the epididymis, and has been implicated in sperm maturation and function. Recent studies suggest that CRISP3 may also play a significant role in immune responses, inflammation, and cancer biology, indicating its involvement in a wider array of biological systems. The protein exhibits several functional characteristics, including interaction with glycosaminoglycans and cytokines, which influence cell signaling pathways. Furthermore, its expression levels have been associated with certain diseases, such as prostate cancer, highlighting its potential as a biomarker or therapeutic target. Understanding the structure-function relationship of CRISP3 through the study of its recombinant protein is crucial for elucidating its biological roles and mechanisms of action. The development of recombinant CRISP3 not only provides a platform for in-depth functional studies but also aids in the exploration of its therapeutic applications, paving the way for innovative strategies in disease intervention and treatment. Overall, the investigation of CRISP3 recombinant protein offers promising insights into its multifaceted roles in health and disease.












