Analytical Data
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Gene name
PRDM13
- Application
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Alternative Names
PRDM13; PFM10; PR domain zinc finger protein 13; EC 2.1.1.-; PR domain-containing protein 13
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H4Q3
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Expression Region
1-707 aa
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AA Sequence
MHGAARAPAT SVSADCCIPA GLRLGPVPGT FKLGKYLSDR REPGPKKKVR MVRGELVDES GGSPLEWIGL IRAARNSQEQ TLEAIADLPG GQIFYRALRD VQPGEELTVW YSNSLAQWFD IPTTATPTHD EKGEERYICW YCWRTFRYPN SLKAHLRFHC VFSGGGGGAF LHHEHAARQG AVPAADGLGL SPKPPAPDFA APSQAGTLRP HPLGPPPVQA CGAREGIKRE ASSAPSATSP TPGKWGQPKK GKEQLDRALD MSGAARGQGH FLGIVGGSSA GVGSLAFYPG VRSAFKPAGL ARAAAAAHGD PYREESSSKQ GAGLALGRLL GGGRACGRPG SGENSAAGGA GHHHHHHAHH HHHPKCLLAG DPPPPPPPGL PCSGALRGFP LLSVPPEEAS AFKHVERAPP AAAALPGARY AQLPPAPGLP LERCALPPLD PGGLKAYPGG ECSHLPAVMP AFTVYNGELL YGSPATTAYY PLKLHFGGLL KYPESISYFS GPAAAALSPA ELGSLASIDR EIAMHNQQLS EMAAGKGRGR LDSGTLPPAV AAAGGTGGGG SGGSGAGKPK TGHLCLYCGK LYSRKYGLKI HMRTHTGYKP LKCKVCLRPF GDPSNLNKHI RLHAEGNTPY RCEFCGKVLV RRRDLERHVK SRHPGQSLLA KAGDGPGAEP GYPPEPGDPK SDDSDVDVCF TDDQSDPEVG GGGERDL
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Molecular Weight
73.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PRDM13 is a member of the PRDM family of proteins, characterized by the presence of a PR/SET domain, and plays a critical role in various biological processes, particularly in development and differentiation. Recent studies have highlighted its significance in embryonic stem cell regulation and neural lineage commitment, suggesting that PRDM13 might be involved in key pathways governing cell fate decisions. Additionally, research indicates that PRDM13 may function as a transcriptional regulator, influencing gene expression patterns during the early stages of development. Abnormal expression or dysfunction of PRDM13 has been linked to several developmental disorders and could potentially play a role in tumorigenesis. Investigating the recombinant protein of PRDM13 allows researchers to explore its structural and functional properties, offering insights into its mechanistic roles in cellular processes. As the understanding of PRDM13 continues to evolve, elucidating its interactions and regulatory networks will be crucial for uncovering its implications in both normal physiology and disease states, making it a valuable target for further research in developmental biology and cancer therapeutics.
