Analytical Data
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基因名
CORO6
- Application
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别名
CORO6；Coronin-6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6QEF8
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表达区间
1-472aa
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氨基酸序列
MSRRVVRQSK FRHVFGQAAK ADQAYEDIRV SKVTWDSSFC AVNPKFLAII VEAGGGGAFI VLPLAKTGRV DKNYPLVTGH TAPVLDIDWC PHNDNVIASA SDDTTIMVWQ IPDYTPMRNI TEPIITLEGH SKRVGILSWH PTARNVLLSA GGDNVIIIWN VGTGEVLLSL DDMHPDVIHS VCWNSNGSLL ATTCKDKTLR IIDPRKGQVV AEQARPHEGA RPLRAVFTAD GKLLSTGFSR MSERQLALWD PNNFEEPVAL QEMDTSNGVL LPFYDPDSSI VYLCGKGDSS IRYFEITDEP PFVHYLNTFS SKEPQRGMGF MPKRGLDVSK CEIARFYKLH ERKCEPIIMT VPRKSDLFQD DLYPDTPGPE PALEADEWLS GQDAEPVLIS LRDGYVPPKH RELRVTKRNI LDVRPPSGPR RSQSASDAPL SQQHTLETLL EEIKALRERV QAQEQRITAL ENMLCELVDG TD
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CORO6, a member of the coronin protein family, plays a crucial role in various cellular processes, including cytoskeletal dynamics, cell migration, and immune responses. Originally identified in the context of actin-binding proteins, CORO6 is known to interact with the cytoskeleton and participate in the regulation of cellular morphology and movement. Studies have indicated that CORO6 is involved in critical pathways, such as apoptosis and autophagy, highlighting its potential importance in disease mechanisms, particularly in cancer and autoimmune disorders. The interest in CORO6 has surged due to its functional relevance in modulating cellular behaviors and its potential as a therapeutic target. Researchers have pursued the recombinant expression of CORO6 to investigate its structural properties and functional capabilities, employing techniques such as protein purification and functional assays. Understanding CORO6's structure and interaction partners can offer insights into its role in health and disease, paving the way for novel intervention strategies targeting its pathways. As such, the recombinant CORO6 protein serves as an essential tool for deciphering its biological functions and exploring its potential applications in biomedical research and therapeutic development.
