Analytical Data
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基因名
C13orf3
- Application
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别名
C13orf3; RAMA1; SKA3; SKA3_HUMAN; Spindle and kinetochore associated complex subunit 3; Spindle and kinetochore-associated Protein 3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IX90
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表达区间
1-303aa
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氨基酸序列
MAGAACEPVARPSLTSISSGELRSLWTCDCELALLPLAQLLRLQPGAFQLSGDQLVVAGPGEPAAARGGFNVFGDGLVRLDGQLYRLSSYIKRYVELTNYCDYKDYRETILSKPMLFFINVQTKKDTSKERTYAFLVNTRHPKIRRQIEQGMDMVISSVIGESYRLQFDFQEAVKNFFPPGNEVVNGENLSFAYEFKADALFDFFYWFGLSNSVVKVNGKVLNLSSTSPEKKETIKLFLEKMSEPLIRRSSFSDRKFSVTSRGSIDDVFNCNLSPRSSLTEPLLAELPFPSVLESEETPNQFI
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分子量
60.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C13orf3, also known as Chromosome 13 open reading frame 3, has garnered attention in recent years due to its potential implications in various biological processes and diseases, including cancer. Initially identified as a gene located on chromosome 13, studies have suggested that C13orf3 may play a role in regulating cell proliferation and apoptosis. Its expression levels have been found to be altered in several tumor types, indicating a possible involvement in tumorigenesis and cancer progression. Additionally, C13orf3 has been implicated in immune response modulation, highlighting its relevance in autoimmune diseases. Given the poorly understood functional mechanisms of C13orf3, research efforts have increasingly focused on generating recombinant proteins for in-depth biochemical characterization. Recombinant C13orf3 proteins can be utilized to elucidate its structure-function relationships, investigate its interactions with other cellular proteins, and evaluate its biological activity in vitro and in vivo. These studies are critical for establishing a comprehensive understanding of the molecular pathways involving C13orf3 and may pave the way for developing targeted therapies for diseases associated with its dysregulation. By advancing our knowledge of C13orf3, researchers aim to clarify its role in health and disease and explore its potential as a biomarker or therapeutic target in clinical settings.
