Analytical Data
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基因名
C11orf42
- Application
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别名
C11orf42Uncharacterized Protein C11orf42
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N5U0
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表达区间
1-333aa
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氨基酸序列
MLVGTPNLLT LDEADATWTL IKDKVIEEHF GPNAVAVPFL SDAACYDLLG VLVKQSRPAH TRLALPGRQG RRALKPVGPL PSLLEQAGSE GAFAHCTREY SPNGRAERAY EETRMLDGQP CKIRLHMGDL RKKVAFLLLP PGQVSLQQTL PWLRSTHSIY VIYQVFSCSW LQLGLTSTAR EPQLLRLLRS LPVAFSCLKF SLQSKGVLGP QKPLTKDPLP HGANWVRPNL SIMPPLAPTS APADTTEAAD VPPPVPAPPT PPPQEGPEDK PTRFSYKGRN PFWRGPQILS ENWLFSPRSP PPGAQGGGPR DPDGHSMSLP LLQGLSSEFD SDD
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分子量
62.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C11orf42, also known as "SENP1-like protein," is a gene located on chromosome 11 that is thought to play a role in various cellular processes, including regulation of gene expression and possibly influencing neurodegenerative diseases. Recent studies have highlighted its potential involvement in the pathogenesis of certain conditions, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Understanding the function of C11orf42 and its resulting recombinant protein is crucial for elucidating the molecular mechanisms underlying these diseases. Researchers have begun to investigate the protein’s structure, interactions, and effects on cellular pathways. By producing a recombinant form of C11orf42, it becomes possible to conduct functional assays and explore its role in cellular stress responses, protein aggregation, and neuroinflammation. Additionally, this research could identify potential therapeutic targets and strategies to combat neurodegeneration. Ultimately, studying C11orf42 recombinant protein aims to clarify its biological significance and contribution to neurodegenerative disease mechanisms, thus paving the way for novel treatment approaches.
