Analytical Data
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Gene name
C11orf42
- Application
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Alternative Names
C11orf42Uncharacterized Protein C11orf42
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N5U0
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Expression Region
1-333aa
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AA Sequence
MLVGTPNLLT LDEADATWTL IKDKVIEEHF GPNAVAVPFL SDAACYDLLG VLVKQSRPAH TRLALPGRQG RRALKPVGPL PSLLEQAGSE GAFAHCTREY SPNGRAERAY EETRMLDGQP CKIRLHMGDL RKKVAFLLLP PGQVSLQQTL PWLRSTHSIY VIYQVFSCSW LQLGLTSTAR EPQLLRLLRS LPVAFSCLKF SLQSKGVLGP QKPLTKDPLP HGANWVRPNL SIMPPLAPTS APADTTEAAD VPPPVPAPPT PPPQEGPEDK PTRFSYKGRN PFWRGPQILS ENWLFSPRSP PPGAQGGGPR DPDGHSMSLP LLQGLSSEFD SDD
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Molecular Weight
62.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C11orf42, also known as "SENP1-like protein," is a gene located on chromosome 11 that is thought to play a role in various cellular processes, including regulation of gene expression and possibly influencing neurodegenerative diseases. Recent studies have highlighted its potential involvement in the pathogenesis of certain conditions, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Understanding the function of C11orf42 and its resulting recombinant protein is crucial for elucidating the molecular mechanisms underlying these diseases. Researchers have begun to investigate the protein’s structure, interactions, and effects on cellular pathways. By producing a recombinant form of C11orf42, it becomes possible to conduct functional assays and explore its role in cellular stress responses, protein aggregation, and neuroinflammation. Additionally, this research could identify potential therapeutic targets and strategies to combat neurodegeneration. Ultimately, studying C11orf42 recombinant protein aims to clarify its biological significance and contribution to neurodegenerative disease mechanisms, thus paving the way for novel treatment approaches.











